Publications

2022

  • Lebwohl, M., Kim, B., Goncalves, J., Nograles, K., Munera, C. and Guttman-Yassky, E., 2022, September. Oral difelikefalin improves itch and quality of life in subjects with itch-dominant atopic dermatitis: subgroup analysis of a randomized phase II study. In BRITISH JOURNAL OF DERMATOLOGY (Vol. 187, No. 3, pp. E114-E116). 111 RIVER ST, HOBOKEN 07030-5774, NJ USA: WILEY.
  • Guttman-Yassky, E., Facheris, P., Da Rosa, J.C., Estrada, Y., David, E., Pavel, A., Bose, S., Goncalves, J., Nograles, K., Kim, B. and Lebwohl, M., 2022, September. Oral difelikefalin improves itch and inflammatory biomarkers in subjects with atopic dermatitis with moderate-to-severe pruritus. In BRITISH JOURNAL OF DERMATOLOGY (Vol. 187, No. 3, pp. E116-E116). 111 RIVER ST, HOBOKEN 07030-5774, NJ USA: WILEY.
  • Thyssen, J.P., Bewley, A., Staender, S., Castro, C., Misery, L., Kim, B., Biswas, P., Chan, G., Myers, D.E., Watkins, M. and Alderfer, J., 2022, September. Abrocitinib reduces skin pain in adolescent and adult patients with moderate-to-severe atopic dermatitis. In BRITISH JOURNAL OF DERMATOLOGY (Vol. 187, No. 3, pp. E118-E118). 111 RIVER ST, HOBOKEN 07030-5774, NJ USA: WILEY.
  • Dong X, Limjunyawong N, Sypek EI, Wang G, Ortines RV, Youn C, Alphonse MP, Dikeman D, Wang Y, Lay M, Kothari R, Vasavda C, Pundir P, Goff L, Miller LS, Lu W, Garza LA, Kim BS, Archer NK, Dong X. Keratinocyte-derived defensins activate neutrophil-specific receptors Mrgpra2a/b to prevent skin dysbiosis and bacterial infection. Immunity. 2022 Sep 13;55(9):1645-1662.e7. doi: 10.1016/j.immuni.2022.06.021. Epub 2022 Jul 25. PMID: 35882236; PMCID: PMC9474599.
  • J.P. Thyssen, A. Bewley, S. Ständer, C. Castro, L. Misery, B. Kim, P. Biswas, G. Chan, D.E. Myers, M. Watkins, J. Alderfer, E. Guler, J.I. Silverberg, L’abrocitinib réduit les douleurs cutanées chez les patients adolescents et adultes atteints de dermatite atopique modérée à sévère, Annales de Dermatologie et de Vénéréologie – FMC, Volume 2, Issue 8, Supplement 1,
  • Kim, B. S., Bissonnette, R., Nograles, K., Munera, C., Shah, N., Jebara, A., Cirulli, J., Goncalves, J., & Lebwohl, M. (2022). A Phase 2 Study of Oral Difelikefalin for Moderate-to-Severe Pruritus in Subjects With Notalgia Paresthetica (KOMFORT). SKIN The Journal of Cutaneous Medicine, 6(6), s104. https://doi.org/10.25251/skin.6.supp.104
  • Anna M Trier , Brian S Kim, Insights into atopic dermatitis pathogenesis lead to newly approved systemic therapies, British Journal of Dermatology, Volume 188, Issue 6, June 2023, Pages 698–708, https://doi.org/10.1093/bjd/ljac016
  • Kim BS, Inan S, Ständer S, Sciascia T, Szepietowski JC, Yosipovitch G. Role of kappa-opioid and mu-opioid receptors in pruritus: Peripheral and central itch circuits. Exp Dermatol. 2022 Dec;31(12):1900-1907. doi: 10.1111/exd.14669. Epub 2022 Sep 23. PMID: 36054458; PMCID: PMC10087456.
  • Mamuladze T, Kim BS. The Sensation of Itch: From Biological Discovery to Medical Treatment. J Invest Dermatol. 2022 Jan;142(1):21-22. doi: 10.1016/j.jid.2021.10.023. Epub 2021 Nov 18. PMID: 34801533.
  • Shibuya R, Kim BS. Skin-homing basophils and beyond. Front Immunol. 2022;13 1059098. doi:10.3389/fimmu.2022.1059098. PMID: 36618424; PMCID: PMC9815541.
  • Blauvelt, A., de Bruin-Weller, M.S., Kwatra, S.G., Gooderham, M.J., Kim, B., Liu, Y., Chu, A., Oforia, S., Platt, A., Calimlim, B. and Silverberg, J.I., 2022, January. EFFICACY OF UPADACITINIB VS DUPILUMAB FOR MODERATE-TO-SEVERE ATOPIC DERMATITIS: ANALYSIS OF TIME SPENT IN ITCH RESPONSE STATE FROM THE HEADS UP STUDY. In ACTA DERMATO-VENEREOLOGICA (Vol. 102, pp. 21-21).
  • Trier AM, Mack MR, Fredman A, Tamari M, Ver Heul AM, Zhao Y, Guo CJ, Avraham O, Ford ZK, Oetjen LK, Feng J, Dehner C, Coble D, Badic A, Joshita S, Kubo M, Gereau RW 4th, Alexander-Brett J, Cavalli V, Davidson S, Hu H, Liu Q, Kim BS. IL-33 signaling in sensory neurons promotes dry skin itch. J Allergy Clin Immunol. 2022 Apr;149(4):1473-1480.e6. doi: 10.1016/j.jaci.2021.09.014. Epub 2021 Sep 21. PMID: 34560104; PMCID: PMC8934751.
  • Wei C, Kim B, McKemy DD. Transient receptor potential melastatin 8 is required for nitroglycerin- and calcitonin gene-related peptide-induced migraine-like pain behaviors in mice. Pain. 2022 Dec 1;163(12):2380-2389. doi: 10.1097/j.pain.0000000000002635. Epub 2022 Mar 29. PMID: 35353773; PMCID: PMC9519811.
  • Trier AM, Mack MR, Fredman A, Tamari M, Ver Heul AM, Zhao Y, Guo CJ, Avraham O, Ford ZK, Oetjen LK, Feng J, Dehner C, Coble D, Badic A, Joshita S, Kubo M, Gereau RW 4th, Alexander-Brett J, Cavalli V, Davidson S, Hu H, Liu Q, Kim BS. IL-33 signaling in sensory neurons promotes dry skin itch. J Allergy Clin Immunol. 2022 Apr;149(4):1473-1480.e6. doi: 10.1016/j.jaci.2021.09.014. Epub 2021 Sep 21. PMID: 34560104; PMCID: PMC8934751.
  • Trier AM, Kim BS. Structural insights into MRGPRX2: A new vision of itch and allergy. J Allergy Clin Immunol. 2022 Apr;149(4):1221-1222. doi: 10.1016/j.jaci.2022.01.017. Epub 2022 Jan 26. PMID: 35090947.
  • Kim, B.S., Tamari, M., Zamidar, L., Nograles, K., Munera, C., Goncalves, J., Guttman-Yassky, E. and Lebwohl, M., 2022, April. Oral difelikefalin reduces pruritus in atopic dermatitis. In BRITISH JOURNAL OF DERMATOLOGY (Vol. 186, No. 4, pp. E135-E136). 111 RIVER ST, HOBOKEN 07030-5774, NJ USA: WILEY.
  • Thyssen, J.P., Bewley, A., Stander, S., Kim, B., Biswas, P., DiBonaventura, M., Watkins, M., Alderfer, J., Guler, E. and Silverberg, J.I., 2022, April. Rapid and sustained improvement in skin pain with abrocitinib in adult and adolescent patients with moderate-to-severe atopic dermatitis. In BRITISH JOURNAL OF DERMATOLOGY (Vol. 186, No. 4, pp. E150-E151). 111 RIVER ST, HOBOKEN 07030-5774, NJ USA: WILEY.
  • Jeon J, Wang F, Badic A, Kim BS. Treatment of patients with chronic pruritus of unknown origin with dupilumab. J Dermatolog Treat. 2022 May;33(3):1754-1757. doi: 10.1080/09546634.2021.1880542. Epub 2021 Feb 8. PMID: 33557654.
  • Kim BS. The translational revolution of itch. Neuron. 2022 Jul 20;110(14):2209-2214. doi: 10.1016/j.neuron.2022.03.031. Epub 2022 Apr 20. PMID: 35447089; PMCID: PMC9308644.
  • Feng J, Zhao Y, Xie Z, Zang K, Sviben S, Hu X, Fitzpatrick JAJ, Wen L, Liu Y, Wang T, Lawson K, Liu Q, Yan Y, Dong X, Han L, Wu GF, Kim BS, Hu H. Miswiring of Merkel cell and pruriceptive C fiber drives the itch-scratch cycle. Sci Transl Med. 2022 Jul 13;14(653):eabn4819. doi: 10.1126/scitranslmed.abn4819. Epub 2022 Jul 13. PMID: 35857641; PMCID: PMC9888006.
  • Guttman-Yassky, E., Facheris, P., Da Rosa, J.C., Del Duca, E., Estrada, Y., David, E., Pavel, A., Bose, S., Goncalves, J., Nograles, K. and Kim, B., 2022. 299 Oral difelikefalin improves itch and inflammatory biomarkers in atopic dermatitis subjects with moderate-to-severe pruritus. Journal of Investigative Dermatology, 142(8), p.S51.
  • Trier, A. M., Ver Heul, A., Fredman, A., Meixong, J., Wang, F., Dong, X., & Kim, B. (2022). LB982 IL-33 enhancement of histaminergic itch is dependent on IL-13. Journal of Investigative Dermatology, 142(8), B25.

2021

2020

2019

2018

2017

  • Oetjen LK, Mack MR, Feng J, Whelan TM, Niu H, Guo CJ, Chen S, Trier AM, Xu AZ, Tripathi SV, Luo J, Gao X, Yang L, Hamilton SL, Wang PL, Brestoff JR, Council ML, Brasington R, Schaffer A, Brombacher F, Hsieh CS, Gereau RW 4th, Miller MJ, Chen ZF, Hu H, Davidson S, Liu Q, Kim BS. Sensory Neurons Co-opt Classical Immune Signaling Pathways to Mediate Chronic Itch. Cell. 2017 Sep 21;171(1):217-228.e13. doi: 10.1016/j.cell.2017.08.006. Epub 2017 Sep 7. PubMed PMID: 28890086; PubMed Central PMCID: PMC5658016. PlumX Metrics 
  • Feng J, Yang P, Mack MR, Dryn D, Luo J, Gong X, Liu S, Oetjen LK, Zholos AV, Mei Z, Yin S, Kim BS, Hu H. Sensory TRP channels contribute differentially to skin inflammation and persistent itch. Nat Commun. 2017 Oct 30;8(1):980. doi: 10.1038/s41467-017-01056-8. PubMed PMID: 29081531; PubMed Central PMCID: PMC5661746. 
  • Feng J, Luo J, Mack MR, Yang P, Zhang F, Wang G, Gong X, Cai T, Mei Z, Kim BS, Yin S, Hu H. The antimicrobial peptide human beta-defensin 2 promotes itch through Toll-like receptor 4 signaling in mice. J Allergy Clin Immunol. 2017 Sep;140(3):885-888.e6. doi: 10.1016/j.jaci.2017.03.035. Epub 2017 Apr 23. PubMed PMID: 28442325; PubMed Central PMCID: PMC5591760. 
  • Ma CA, Stinson JR, Zhang Y, Abbott JK, Weinreich MA, Hauk PJ, Reynolds PR, Lyons JJ, Nelson CG, Ruffo E, Dorjbal B, Glauzy S, Yamakawa N, Arjunaraja S, Voss K, Stoddard J, Niemela J, Zhang Y, Rosenzweig SD, McElwee JJ, DiMaggio T, Matthews HF, Jones N, Stone KD, Palma A, Oleastro M, Prieto E, Bernasconi AR, Dubra G, Danielian S, Zaiat J, Marti MA, Kim B, Cooper MA, Romberg N, Meffre E, Gelfand EW, Snow AL, Milner JD. Germline hypomorphic CARD11 mutations in severe atopic disease. Nat Genet. 2017 Aug;49(8):1192-1201. doi: 10.1038/ng.3898. Epub 2017 Jun 19. PubMed PMID: 28628108; PubMed Central PMCID: PMC5664152. 
  • Leichner TM, Satake A, Harrison VS, Tanaka Y, Archambault AS, Kim BS, Siracusa MC, Leonard WJ, Naji A, Wu GF, Artis D, Kambayashi T. Skin-derived TSLP systemically expands regulatory T cells. J Autoimmun. 2017 May;79:39-52. doi: 10.1016/j.jaut.2017.01.003. Epub 2017 Jan 23. PubMed PMID: 28126203; PubMed Central PMCID: PMC5386815. 

2016

2015

2014

2013

2012 and Before