Our trainees have published in high-impact journals, given podium presentations at multiple national meetings, and directly informed the delivery of care to patients with allergic and chronic pruritic disorders.

A World Class Team

Meet Our Team

Our program encompasses everything from molecular discovery to phase 3 clinical trials. Therefore, all of our studies are performed with the central mission of translating our scientific observations to treating diseases in patients. Given our unique expertise in type 2 immunity and neuroimmunology, we are also able to inform emerging, new, and existing therapies for allergic and chronic pruritic disorders.

Translational Medicine

A combination of hypothesis-driven and unbiased discovery-based science. We employ a variety of techniques including in vivo mouse modeling, behavioral assays, and high-throughput single cell sequencing, and multidimensional flow and mass cytometry to identify new therapeutic targets for the clinic.

Cutting Edge Neuroimmunology

View Our Publications

Chronic itch disorders such as atopic dermatitis have a handful of effective treatments available. In our Itch Clinic, we take a highly personalized approach to our evaluation of patients with chronic itch.

Internationally Recognized Specialty Itch Clinic

View Our Studies

Brian Kim Lab

Services

The Kim Lab has unique expertise in basic approaches and techniques in innate immunity, neuroimmunology, and behavioral modeling of chronic itch. Additionally, we actively design translational, clinical research studies, and interventional clinical trials. Thus, we are able to provide state-of-the-art guidance on everything from in vitro studies to phase 3 clinical trials to better understand cutaneous immunity, inflammation, and itch.

Translational Science and Medicine

Mechanistic cellular and molecular studies in the Kim Lab are efficiently tested and validated in human cells and tissues. Further, we employ preclinical modeling of human disease to test candidate targets, pathways, and drugs to quickly inform drug development. Thus, we are able to provide expertise in early stage drug development to biotechnology companies and CROs with regard to mechanism of action, route of delivery, and optimization of therapy.

Basic Science

The Kim Lab has unique expertise in basic approaches and techniques in innate immunity, neuroimmunology, and behavioral modelling of chronic itch. Therefore, we are able to provide state of the art guidance on in vitro, ex vivo, and in vivo experimental systems to better understand skin immunity, inflammation, and sensation.

Diagnostics

The Itch Clinic sees many different forms of chronic itch disorders. As a result, we have discovered new genetic mutations, syndromes, and diseases that present as chronic itch. Thus, we have opportunities to discover new disorders and develop novel diagnostics for various chronic itch disorders.

Clinical Trials

Treatments for chronic itch disorders are currently very limited due to lack of effective medications currently on the market. Therefore, we often take a personalized approach with off-label use of medications. Additionally, we have active clinical trials that patients can participate in pending qualification.

We have active clinical trials ongoing for patients with Chronic Pruritus of Unknown Origin (CPUO) or itch of unknown cause. If you have been diagnosed with or feel you may have this condition, please contact our Asima Badic, RMA at (314) 273-1376.

We have active clinical trials ongoing for patients with Prurigo Nodularis (PN). If you have been diagnosed with or feel you may have this condition, please contact our Asima Badic, RMA at (314) 273-1376.

We have active clinical trials ongoing for patients with Notalgia Paresthetica (NP). If you have been diagnosed with or feel you may have this condition, please contact our Asima Badic, RMA at (314) 273-1376.

We have active clinical trials ongoing for patients with Atopic Dermatitis (AD) or Eczema. If you have been diagnosed with or feel you may have this condition, please contact our Asima Badic, RMA at (314) 273-1376.

Testimonials

What Our Collaborators and Patients Say

Our Team

Scientists

Masato Tamari, MD, PhD

Masato Tamari, MD, PhD

Dr. Tamari is a pediatric allergy and immunology specialist from Jikei University in Tokyo, Japan. He is studying not cytokines regulate neuronal responses in the skin and lung.

Lydia Zamidar

Lydia Zamidar

Lydia received her B.S. in Biology from Cornell University and aspires to go to graduate school. She is a superstar technician in the Kim Lab.

Aaron Ver Heul, MD, PhD

Aaron Ver Heul, MD, PhD

Received MD/PhD from the University of Iowa and is currently studying neuroimmunologic mechanisms that underlie atopic disease.
Instructor of Medicine in the Division of Allergy and Immunology.

Pamela Gassner

Pamela Gassner

Administrator

Pamela Gassner has been an integral member of the Division of Dermatology for 18 years and is the administrator for all Kim Lab activities. She manages many aspects of the the program including federal grant submissions, budgeting, sponsored research agreements, scheduling, and conference organization.

Latest News

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Our Research

Howard Hughes Medical Institute (HHMI) Medical Fellow and WUSM MD/MA student, Amy Xu, discusses her experience and research on chronic itch.

Industry Partners

The Kim Lab has diverse partnerships with innovative biotechnology and pharmaceutical companies that are interested in inflammatory skin and chronic itch disorders. These collaborations help us to rapidly translate our basic science research into clinical trials to help patients suffering from diseases such as atopic dermatitis.

 

Incyte
LEO
Cara Therapeutics

Sponsored Research

If you are interested in specific sponsored research activities with the Kim Lab, please contact us.

Support Our Science

Some of the greatest discoveries in biomedical research came through direct donations from generous individuals. The Kim Lab is grateful for the support it has received from philanthropic donors. If you are interested giving, please reach out to us. Please be sure to specifically assign the donation to the Brian Kim Lab or Clinical Center for Itch or Mark Lebwohl Center for Neuroinflammation and Sensation.

FAQ

Barnes-Jewish Hospital

Center for Outpatient Health

4901 Forest Park Avenue

5th Floor

St. Louis, MO 63108

The Itch Clinic is open on Mondays from 12:30 pm – 5 :00 pm.

Treatments for chronic itch disorders are currently very limited due to lack of effective medications currently on the market. Therefore, we take a personalized approach with off-label use of medications. Additionally, we have active clinical trials that patients can participate in pending qualification.

The Kimberly and Eric J. Waldman Department of Dermatology

Icahn School of Medicine at Mount Sinai

1425 Madison Avenue, Box 1047

New York, NY 10029-6574

T: 212-659-9530