Madison Mack

Madison is currently pursuing a Ph.D. degree in immunology and is interested in how systemic innate immune dysregulation may be a critically important feature of atopic dermatitis in patients.

Hometown: St. Louis, MO

High School: Webster Groves High School

College: Macalester College

Degree: B.A. in Biology


AAI Trainee Abstract Travel Award, 2018
NSF Graduate Research Fellowship Program Honorable Mention, 2016 & 2017
Robert A. Uppgren Memorial Endowed Fellowship, 2010-2012
Macalester Faculty Staff Endowed Fellowship, 2010-2011


Luo J, Feng J, Yu G, Yang P, Mack MR, Du J, Yu W, Qian A, Zhang Y, Liu S, Yin S,
Xu A, Cheng J, Liu Q, O’Neil RG, Xia Y, Ma L, Carlton SM, Kim BS, Renner K, Liu
Q, Hu H. Transient receptor potential vanilloid 4-expressing macrophages and
keratinocytes contribute differentially to allergic and nonallergic chronic itch.
The Journal of Allergy and Clinical Immunology. 2018; 141(2):608-619.e7.

Feng J, Luo J, Mack MR, Yang P, Zhang F, Wang G, Gong X, Cai T, Mei Z, Kim BS,
Yin S, Hu H. The antimicrobial peptide human beta-defensin 2 promotes itch
through Toll-like receptor 4 signaling in mice. The Journal of Allergy and
Clinical Immunology. 2017; 140(3):885-888.e6.

Oetjen LK, Mack MR, Feng J, Whelan TM, Niu H, Guo CJ, Chen S, Trier AM, Xu AZ,
Tripathi SV, Luo J, Gao X, Yang L, Hamilton SL, Wang PL, Brestoff JR, Council ML,
Brasington R, Schaffer A, Brombacher F, Hsieh CS, Gereau RW 4th, Miller MJ, Chen
ZF, Hu H, Davidson S, Liu Q, Kim BS. Sensory Neurons Co-opt Classical Immune
Signaling Pathways to Mediate Chronic Itch. Cell. 2017; 171(1):217-228.e13.

Yang P, Feng J, Luo J, Madison M, Hu H. A Critical Role for TRP Channels in the
Skin 2nd ed. Emir TLR, editor. Boca Raton (FL): CRC Press/Taylor & Francis;2017. Chapter 6.

Feng J, Yang P, Mack MR, Dryn D, Luo J, Gong X, Liu S, Oetjen LK, Zholos AV, Mei
Z, Yin S, Kim BS, Hu H. Sensory TRP channels contribute differentially to skin
inflammation and persistent itch. Nature Communications. 2017; 8(1):980.

Mack MR, Kim BS. Superficial Immunity: Antimicrobial Responses Are More Than Skin
Deep. Immunity. 2016; 45(1):6-8.

Manieri NA, Mack MR, Himmelrich MD, Worthley DL, Hanson EM, Eckmann L, Wang TC,
Stappenbeck TS. Mucosally transplanted mesenchymal stem cells stimulate
intestinal healing by promoting angiogenesis. The Journal of Clinical
Investigation. 2015; 125(9):3606-18.

Mack MR, Wendelschafer-Crabb G, McAdams BD, Hordinsky MK, Kennedy WR, Tolar J.
Peripheral neuro-immune pathology in recessive dystrophic epidermolysis bullosa.
The Journal of Investigative Dermatology. 2015; 135(4):1193-1197.

Mack M, Tonc E, Ashbaugh A, Wetzel A, Sykes A, Engblom C, Shabani E, Mora-Solano
C, Trier A, Swanson L, Ewan E, Martinov T, Chatterjea D. Clonal differences in
IgE antibodies affect cutaneous anaphylaxis-associated thermal sensitivity in
mice. Immunology Letters. 2014; 162(1 Pt A):149-58.

Martinov T, Mack M, Sykes A, Chatterjea D. Measuring changes in tactile
sensitivity in the hind paw of mice using an electronic von Frey apparatus.
Journal of visualized experiments : Journal of Visualized Experiments. 2013; (82):e51212.

Chatterjea D, Wetzel A, Mack M, Engblom C, Allen J, Mora-Solano C, Paredes L,
Balsells E, Martinov T. Mast cell degranulation mediates compound 48/80-induced
hyperalgesia in mice. Biochemical and Biophysical Research Communications. 2012;