Publications

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We publish regularly in journals that cover a range of topics from discovery-based basic science and first-in-human translational medicine to  large randomized clinical trials. Please see below for a representative list of our publications.

2021

A Basophil-Neuronal Axis Promotes Itch. Wang F, Trier AM, Li F, Kim S, Chen Z, Chai JN, Mack MR, Morrison SA, Hamilton JD, Baek J, Yang TB, Ver Heul AM, Xu AZ, Xie Z, Dong X, Kubo M, Hu H, Hsieh CS, Dong X, Liu Q, Margolis DJ, Ardeleanu M, Miller MJ, Kim BS. Cell. 2021 Jan 21;184(2):422-440.e17. doi: 10.1016/j.cell.2020.12.033. Epub 2021 Jan 14. PMID: 33450207 PlumX Metrics

IL-33 signaling in sensory neurons promotes dry skin itch. Trier AM, Mack MR, Fredman A, Tamari M, Ver Heul AM, Zhao Y, Guo CJ, Avraham O, Ford ZK, Oetjen LK, Feng J, Dehner C, Coble D, Badic A, Joshita S, Kubo M, Gereau RW 4th, Alexander-Brett J, Cavalli V, Davidson S, Hu H, Liu Q, Kim BS. J Allergy Clin Immunol. 2021 Sep 21:S0091-6749(21)01405-6. doi: 10.1016/j.jaci.2021.09.014.

Sneezing reflex is mediated by a peptidergic pathway from nose to brainstem. Li F, Jiang H, Shen X, Yang W, Guo C, Wang Z, Xiao M, Cui L, Luo W, Kim BS, Chen Z, Huang AJW, Liu Q. Cell. 2021 Jul 8;184(14):3762-3773.e10. doi: 10.1016/j.cell.2021.05.017. Epub 2021 Jun 15. PMID: 34133943

Thymic stromal lymphopoietin induces adipose loss through sebum hypersecretion. Choa R, Tohyama J, Wada S, Meng H, Hu J, Okumura M, May RM, Robertson TF, Pai RL, Nace A, Hopkins C, Jacobsen EA, Haldar M, FitzGerald GA, Behrens EM, Minn AJ, Seale P, Cotsarelis G, Kim B, Seykora JT, Li M, Arany Z, Kambayashi T. Science. 2021 Jul 30;373(6554):eabd2893. doi: 10.1126/science.abd2893. PMID: 34326208

Immunosensation: Neuroimmune Cross Talk in the Skin. Tamari M, Ver Heul AM, Kim BS. Annu Rev Immunol. 2021 Apr 26;39:369-393. doi: 10.1146/annurev-immunol-101719-113805. Epub 2021 Feb 9. PMID: 33561366

Bidirectional sensory neuron-immune interactions: a new vision in the understanding of allergic inflammation. Tauber M, Wang F, Kim B, Gaudenzio N. Curr Opin Immunol. 2021 Oct;72:79-86. doi: 10.1016/j.coi.2021.03.012. Epub 2021 Apr 17. PMID: 33873125

Beyond somatosensation: Mrgprs in mucosal tissues. Inclan-Rico JM, Kim BS, Abdus-Saboor I. Neurosci Lett. 2021 Mar 23;748:135689. doi: 10.1016/j.neulet.2021.135689. Epub 2021 Feb 11. PMID: 33582191

Rapid Improvement of Itch Associated With Atopic Dermatitis With Abrocitinib Is Partially Independent of Overall Disease Improvement: Results From Pooled Phase 2b and 3 Monotherapy Studies. Kim BS, Silverberg JI, Ständer S, Yosipovitch G, Simpson EL, DiBonaventura M, Kerkmann U, Farooqui SA, Biswas P, Valdez H, Cameron MC. Dermatitis. 2021 Oct 1;32(1S):S39-S44. doi: 10.1097/DER.0000000000000770. PMID: 34175862

Mechanosensitive TRPV4 is required for crystal-induced inflammation. Lan Z, Chen L, Feng J, Xie Z, Liu Z, Wang F, Liu P, Yue X, Du L, Zhao Y, Yang P, Luo J, Zhu Z, Hu X, Cao L, Lu P, Sah R, Lavine K, Kim B, Hu H. Ann Rheum Dis. 2021 Dec;80(12):1604-1614. doi: 10.1136/annrheumdis-2021-220295. Epub 2021 Oct 18. PMID: 34663597

Emerging targeted therapeutics underscore immunologic heterogeneity of asthma. Tamari M, Trier AM, Kim BS. J Allergy Clin Immunol. 2021 Sep;148(3):719-721. doi: 10.1016/j.jaci.2021.07.008. Epub 2021 Jul 23. PMID: 34310926

Innate Immune Regulation of Dermatitis. Abreu D, Kim BS. Immunol Allergy Clin North Am. 2021 Aug;41(3):347-359. doi: 10.1016/j.iac.2021.04.011. Epub 2021 Jun 5. PMID: 34225893

Intercellular Mitochondria Transfer to Macrophages Regulates White Adipose Tissue Homeostasis and Is Impaired in Obesity. Brestoff JR, Wilen CB, Moley JR, Li Y, Zou W, Malvin NP, Rowen MN, Saunders BT, Ma H, Mack MR, Hykes BL Jr, Balce DR, Orvedahl A, Williams JW, Rohatgi N, Wang X, McAllaster MR, Handley SA, Kim BS, Doench JG, Zinselmeyer BH, Diamond MS, Virgin HW, Gelman AE, Teitelbaum SL. Cell Metab. 2021 Feb 2;33(2):270-282.e8. doi: 10.1016/j.cmet.2020.11.008. Epub 2020 Dec 4. PMID: 33278339 PlumX Metrics

New and Emerging Treatments for Inflammatory Itch. Erickson S, Heul AV, Kim BS. Ann Allergy Asthma Immunol. 2021 Jan;126(1):13-20. doi: 10.1016/j.anai.2020.05.028. Epub 2020 Jun 1. PMID: 32497711 PlumX Metrics

Treatment of Patients with Chronic Pruritus of Unknown Origin with Dupilumab. Jeon J, Wang F, Badic A, and Kim BS. J Dermatolog Treatment. 2021 Feb 8:1-4. doi: 10.1080/09546634.2021.1880542. Online ahead of print. PMID: 33557654

HLA Class I Polymorphisms Influencing Both Peptide Binding and KIR Interactions Are Associated with Remission among Children with Atopic Dermatitis: A Longitudinal Study. Margolis DJ, Mitra N, Kim BS, Duke JL, Berna RA, Hoffstad OJ, Wasserman JR, Ferriola DA, Mosbruger TL, Wubbenhorst BS, Nathanson KL, Monos DS. J Immunol. 2021 May 1;206(9):2038-2044. doi: 10.4049/jimmunol.2001252. Epub 2021 Apr 16. PMID: 33863792

Human leukocyte antigen class-I variation is associated with atopic dermatitis: A case-control study. Margolis DJ, Mitra N, Duke JL, Berna R, Margolis JD, Hoffstad O, Kim BS, Yan AC, Zaenglein AL, Chiesa Fuxench Z, Dinou A, Wasserman J, Tairis N, Mosbruger TL, Ferriola D, Damianos G, Kotsopoulou I, Monos DS. Hum Immunol. 2021 Aug;82(8):593-599. doi: 10.1016/j.humimm.2021.04.001. Epub 2021 Apr 17. PMID: 33875297

Ethnic variations in scalp pruritus and hair loss. Osemwota O, Herbosa CM, Zhong C, Kwatra SG, Kim BS, Semenov YR. J Am Acad Dermatol. 2021 Mar;84(3):792-794. doi: 10.1016/j.jaad.2020.05.116. Epub 2020 May 30. PMID: 32485212

2020

Itch: A Paradigm of Neuroimmune Crosstalk. Wang F, Kim BS. Immunity. 2020 May 19;52(5):753-766. doi: 10.1016/j.immuni.2020.04.008. PMID: 32433948 PlumX Metrics

Blood natural killer cell deficiency reveals an immunotherapy strategy for atopic dermatitis. Mack MR, Brestoff JR, Berrien-Elliott MM, Trier AM, Yang TB, McCullen M, Collins PL, Niu H, Bodet ND, Wagner JA, Park E, Xu AZ, Wang F, Chibnall R, Council ML, Heffington C, Kreisel F, Margolis DJ, Sheinbein D, Lovato P, Vivier E, Cella M, Colonna M, Yokoyama WM, Oltz EM, Fehniger TA, Kim BS. Sci Transl Med. 2020 Feb 26;12(532):eaay1005. doi: 10.1126/scitranslmed.aay1005. PMID: 32102931 Altmetric

Treatment of atopic dermatitis with ruxolitinib cream (JAK1/JAK2 inhibitor) or triamcinolone cream. Kim BS, Howell MD, Sun K, Papp K, Nasir A, Kuligowski ME; INCB 18424-206 Study Investigators. J Allergy Clin Immunol. 2020 Feb;145(2):572-582. doi: 10.1016/j.jaci.2019.08.042. Epub 2019 Oct 17. PMID: 31629805 PlumX Metrics

Scratching Beyond the Surface of Itchy Wounds. Yang TB, Kim BS. Immunity. 2020 Aug 18;53(2):235-237. doi: 10.1016/j.immuni.2020.07.016. PMID: 32814020 PlumX Metrics

Effects of ruxolitinib cream on pruritus and quality of life in atopic dermatitis: Results from a phase 2, randomized, dose-ranging, vehicle- and active-controlled study. Kim BS, Sun K, Papp K, Venturanza M, Nasir A, Kuligowski ME. J Am Acad Dermatol. 2020 Jun;82(6):1305-1313. doi: 10.1016/j.jaad.2020.02.009. Epub 2020 Feb 11. PMID: 32057960 PlumX Metrics

Kallikrein 7 Promotes Atopic Dermatitis-Associated Itch Independently of Skin Inflammation. Guo CJ, Mack MR, Oetjen LK, Trier AM, Council ML, Pavel AB, Guttman-Yassky E, Kim BS, Liu Q. J Invest Dermatol. 2020 Jun;140(6):1244-1252.e4. doi: 10.1016/j.jid.2019.10.022. Epub 2019 Dec 26. PMID: 31883963 PlumX Metrics

Evaluation of apremilast in chronic pruritus of unknown origin: A proof-of-concept, phase 2a, open-label, single-arm clinical trial. Clark M, Wang F, Bodet ND, Kim BS. Health Sci Rep. 2020 Apr 23;3(2):e154. doi: 10.1002/hsr2.154. eCollection 2020 Jun. PMID: 32337373

Practical approaches for diagnosis and management of prurigo nodularis: US expert panel consensus. *Elmariah S, *Kim B, Berger T, Chisolm S, Kwatra SG, Mollanazar N, Yosipovitch G. J Am Acad Dermatol. 2020 Jul 15:S0190-9622(20)32189-7. doi: 10.1016/j.jaad.2020.07.025. Online ahead of print. PMID: 32682025 PlumX Metrics

Dupilumab treatment results in early and sustained improvements in itch in adolescents and adults with moderate to severe atopic dermatitis: Analysis of the randomized phase 3 studies SOLO 1 and SOLO 2, AD ADOL, and CHRONOS. Silverberg JI, Yosipovitch G, Simpson EL, Kim BS, Wu JJ, Eckert L, Guillemin I, Chen Z, Ardeleanu M, Bansal A, Kaur M, Rossi AB, Graham NMH, Patel N, Gadkari A. J Am Acad Dermatol. 2020 Jun;82(6):1328-1336. doi: 10.1016/j.jaad.2020.02.060. Epub 2020 Mar 3. PMID: 32135208

PAR2 Mediates Itch via TRPV3 Signaling in Keratinocytes. Zhao J, Munanairi A, Liu XY, Zhang J, Hu L, Hu M, Bu D, Liu L, Xie Z, Kim BS, Yang Y, Chen ZF. J Invest Dermatol. 2020 Aug;140(8):1524-1532. doi: 10.1016/j.jid.2020.01.012. Epub 2020 Jan 29. PMID: 32004565 PlumX Metrics

Perfect timing: circadian rhythms, sleep, and immunity – an NIH workshop summary. Haspel JA, Anafi R, Brown MK, Cermakian N, Depner C, Desplats P, Gelman AE, Haack M, Jelic S, Kim BS, Laposky AD, Lee YC, Mongodin E, Prather AA, Prendergast BJ, Reardon C, Shaw AC, Sengupta S, Szentirmai É, Thakkar M, Walker WE, Solt LA. JCI Insight. 2020 Jan 16;5(1):e131487. doi: 10.1172/jci.insight.131487. PMID: 31941836

2019

Meixiong J, Anderson M, Limjunyawong N, Sabbagh MF, Hu E, Mack MR, Oetjen LK, Wang F, Kim BS, Dong X. Activation of Mast-Cell-Expressed Mas-Related G-Protein-Coupled Receptors Drives Non-histaminergic Itch. Immunity. 2019 May 21;50(5):1163-1171.e5. doi: 10.1016/j.immuni.2019.03.013. Epub 2019 Apr 23. PubMed PMID: 31027996; PubMed Central PMCID: PMC6531358. PlumX Metrics 

Wang F, Morris C, Bodet ND, Kim BS. Treatment of Refractory Chronic Pruritus of Unknown Origin With Tofacitinib in Patients With Rheumatoid Arthritis. JAMA Dermatol. 2019 Sep 18. doi: 10.1001/jamadermatol.2019.2804. Online ahead of print.PMID: 31532472

Sensory Neurons Drive Anticipatory Immunity. Trier AM, Kim BS. Cell. 2019 Aug 8;178(4):771-773. doi: 10.1016/j.cell.2019.07.012. PMID: 31398333 PlumX Metrics

Hussain M, Bonilla-Rosso G, Kwong Chung CKC, Bäriswyl L, Rodriguez MP, Kim BS, Engel P, Noti M. High dietary fat intake induces a microbiota signature that promotes food allergy. J Allergy Clin Immunol. 2019 Jul;144(1):157-170.e8. doi: 10.1016/j.jaci.2019.01.043. Epub 2019 Feb 13. PubMed PMID: 30768991.

Trier AM, Mack MR, Kim BS. The Neuroimmune Axis in Skin Sensation, Inflammation, and Immunity. J Immunol. 2019 May 15;202(10):2829-2835. doi: 10.4049/jimmunol.1801473. Review. PubMed PMID: 31061146; PubMed Central PMCID: PMC6563610.

Davidson WF, Leung DYM, Beck LA, Berin CM, Boguniewicz M, Busse WW, Chatila TA, Geha RS, Gern JE, Guttman-Yassky E, Irvine AD, Kim BS, Kong HH, Lack G, Nadeau KC, Schwaninger J, Simpson A, Simpson EL, Spergel JM, Togias A, Wahn U, Wood RA, Woodfolk JA, Ziegler SF, Plaut M. Report from the National Institute of Allergy and Infectious Diseases workshop on “Atopic dermatitis and the atopic march: Mechanisms and interventions”. J Allergy Clin Immunol. 2019 Mar;143(3):894-913. doi: 10.1016/j.jaci.2019.01.003. Epub 2019 Jan 9. PubMed PMID: 30639346; PubMed Central PMCID: PMC6905466.

Huang LH, Zinselmeyer BH, Chang CH, Saunders BT, Elvington A, Baba O, Broekelmann TJ, Qi L, Rueve JS, Swartz MA, Kim BS, Mecham RP, Wiig H, Thomas MJ, Sorci-Thomas MG, Randolph GJ. Interleukin-17 Drives Interstitial Entrapment of Tissue Lipoproteins in Experimental Psoriasis. Cell Metab. 2019 Feb 5;29(2):475-487.e7. doi: 10.1016/j.cmet.2018.10.006. Epub 2018 Nov 8. PubMed PMID: 30415924; PubMed Central PMCID: PMC6365189.

Erickson S, Kim BS. Research Techniques Made Simple: Itch Measurement in Clinical Trials. J Invest Dermatol. 2019 Feb;139(2):264-269.e1. doi: 10.1016/j.jid.2018.12.004. PubMed PMID: 30665580.

2018

Mack MR, Kim BS. The Itch-Scratch Cycle: A Neuroimmune Perspective. Trends Immunol. 2018 Dec;39(12):980-991. doi: 10.1016/j.it.2018.10.001. Epub 2018 Nov 21. Review. PubMed PMID: 30471983. PlumX Metrics

Luo J, Qian A, Oetjen LK, Yu W, Yang P, Feng J, Xie Z, Liu S, Yin S, Dryn D, Cheng J, Riehl TE, Zholos AV, Stenson WF, Kim BS*, Hu H*. TRPV4 Channel Signaling in Macrophages Promotes Gastrointestinal Motility via Direct Effects on Smooth Muscle Cells. Immunity. 2018 Jul 17;49(1):107-119.e4. doi: 10.1016/j.immuni.2018.04.021. Epub 2018 Jun 26. PubMed PMID: 29958798; PubMed Central PMCID: PMC6051912.

Feng J, Luo J, Yang P, Du J, Kim BS, Hu H. Piezo2 channel-Merkel cell signaling modulates the conversion of touch to itch. Science. 2018 May 4;360(6388):530-533. doi: 10.1126/science.aar5703. PubMed PMID: 29724954; PubMed Central PMCID: PMC6114129.

Kesterson K, Nahmias Z, Brestoff JR, Bodet ND, Kau A, Kim BS. Generalized pruritus relieved by NSAIDs in the setting of mast cell activation syndrome. J Allergy Clin Immunol Pract. 2018 Nov – Dec;6(6):2130-2131. doi: 10.1016/j.jaip.2018.03.002. Epub 2018 Mar 23. PubMed PMID: 29577987; NIHMSID:NIHMS1543467.

Trier AM, Kim BS. Cytokine modulation of atopic itch. Curr Opin Immunol. 2018 Oct;54:7-12. doi: 10.1016/j.coi.2018.05.005. Epub 2018 Jun 21. Review. PubMed PMID: 29935376. PlumX Metrics

Oetjen LK, Kim BS. Interactions of the immune and sensory nervous systems in atopy. FEBS J. 2018 Sep;285(17):3138-3151. doi: 10.1111/febs.14465. Epub 2018 Apr 30. Review. PubMed PMID: 29637705; PubMed Central PMCID: PMC6516504.

Hoye ML, Archambault AS, Gordon TM, Oetjen LK, Cain MD, Klein RS, Crosby SD, Kim BS, Miller TM, Wu GF. MicroRNA signature of central nervous system-infiltrating dendritic cells in an animal model of multiple sclerosis. Immunology. 2018 Sep;155(1):112-122. doi: 10.1111/imm.12934. Epub 2018 May 10. PubMed PMID: 29749614; PubMed Central PMCID: PMC6099169.

Brestoff JR, Tesfazghi MT, Zaydman MA, Jackups R Jr, Kim BS, Scott MG, Gronowski AM, Grossman BJ. The B antigen protects against the development of red meat allergy. J Allergy Clin Immunol Pract. 2018 Sep – Oct;6(5):1790-1791.e3. doi: 10.1016/j.jaip.2018.02.010. Epub 2018 Mar 3. PubMed PMID: 29510233.

Shepherd AJ, Mickle AD, Golden JP, Mack MR, Halabi CM, de Kloet AD, Samineni VK, Kim BS, Krause EG, Gereau RW 4th, Mohapatra DP. Macrophage angiotensin II type 2 receptor triggers neuropathic pain. Proc Natl Acad Sci U S A. 2018 Aug 21;115(34):E8057-E8066. doi: 10.1073/pnas.1721815115. Epub 2018 Aug 6. PubMed PMID: 30082378; PubMed Central PMCID: PMC6112686.

Morris GM, Nahmias ZP, Kim BS. Simultaneous improvement of alopecia universalis and atopic dermatitis in a patient treated with a JAK inhibitor. JAAD Case Rep. 2018 Jul;4(6):515-517. doi: 10.1016/j.jdcr.2017.12.016. eCollection 2018 Jul. PubMed PMID: 30023415; PubMed Central PMCID: PMC6047104.

Margolis DJ, Mitra N, Gochnauer H, Wubbenhorst B, D’Andrea K, Kraya A, Hoffstad O, Gupta J, Kim B, Yan A, Fuxench ZC, Nathanson KL. Uncommon Filaggrin Variants Are Associated with Persistent Atopic Dermatitis in African Americans. J Invest Dermatol. 2018 Jul;138(7):1501-1506. doi: 10.1016/j.jid.2018.01.029. Epub 2018 Feb 8. PubMed PMID: 29428354; PubMed Central PMCID: PMC6272058.

Perry JSA, Russler-Germain EV, Zhou YW, Purtha W, Cooper ML, Choi J, Schroeder MA, Salazar V, Egawa T, Lee BC, Abumrad NA, Kim BS, Anderson MS, DiPersio JF, Hsieh CS. Transfer of Cell-Surface Antigens by Scavenger Receptor CD36 Promotes Thymic Regulatory T Cell Receptor Repertoire Development and Allo-tolerance. Immunity. 2018 Jun 19;48(6):1271. doi: 10.1016/j.immuni.2018.05.011. PubMed PMID: 29924978; PubMed Central PMCID: PMC6015728.

Luo J, Feng J, Yu G, Yang P, Mack MR, Du J, Yu W, Qian A, Zhang Y, Liu S, Yin S, Xu A, Cheng J, Liu Q, O’Neil RG, Xia Y, Ma L, Carlton SM, Kim BS, Renner K, Liu Q, Hu H. Transient receptor potential vanilloid 4-expressing macrophages and keratinocytes contribute differentially to allergic and nonallergic chronic itch. J Allergy Clin Immunol. 2018 Feb;141(2):608-619.e7. doi: 10.1016/j.jaci.2017.05.051. Epub 2017 Aug 11. PubMed PMID: 28807414; PubMed Central PMCID: PMC5799031.

Meisel JS, Sfyroera G, Bartow-McKenney C, Gimblet C, Bugayev J, Horwinski J, Kim B, Brestoff JR, Tyldsley AS, Zheng Q, Hodkinson BP, Artis D, Grice EA. Commensal microbiota modulate gene expression in the skin. Microbiome. 2018 Jan 30;6(1):20. doi: 10.1186/s40168-018-0404-9. PubMed PMID: 29378633; PubMed Central PMCID: PMC5789709.

Hussain M, Borcard L, Walsh KP, Pena Rodriguez M, Mueller C, Kim BS, Kubo M, Artis D, Noti M. Basophil-derived IL-4 promotes epicutaneous antigen sensitization concomitant with the development of food allergy. J Allergy Clin Immunol. 2018 Jan;141(1):223-234.e5. doi: 10.1016/j.jaci.2017.02.035. Epub 2017 Apr 6. PubMed PMID: 28390860.

2017

Oetjen LK, Mack MR, Feng J, Whelan TM, Niu H, Guo CJ, Chen S, Trier AM, Xu AZ, Tripathi SV, Luo J, Gao X, Yang L, Hamilton SL, Wang PL, Brestoff JR, Council ML, Brasington R, Schaffer A, Brombacher F, Hsieh CS, Gereau RW 4th, Miller MJ, Chen ZF, Hu H, Davidson S, Liu Q, Kim BS. Sensory Neurons Co-opt Classical Immune Signaling Pathways to Mediate Chronic Itch. Cell. 2017 Sep 21;171(1):217-228.e13. doi: 10.1016/j.cell.2017.08.006. Epub 2017 Sep 7. PubMed PMID: 28890086; PubMed Central PMCID: PMC5658016. PlumX Metrics

Feng J, Yang P, Mack MR, Dryn D, Luo J, Gong X, Liu S, Oetjen LK, Zholos AV, Mei Z, Yin S, Kim BS, Hu H. Sensory TRP channels contribute differentially to skin inflammation and persistent itch. Nat Commun. 2017 Oct 30;8(1):980. doi: 10.1038/s41467-017-01056-8. PubMed PMID: 29081531; PubMed Central PMCID: PMC5661746.

Feng J, Luo J, Mack MR, Yang P, Zhang F, Wang G, Gong X, Cai T, Mei Z, Kim BS, Yin S, Hu H. The antimicrobial peptide human beta-defensin 2 promotes itch through Toll-like receptor 4 signaling in mice. J Allergy Clin Immunol. 2017 Sep;140(3):885-888.e6. doi: 10.1016/j.jaci.2017.03.035. Epub 2017 Apr 23. PubMed PMID: 28442325; PubMed Central PMCID: PMC5591760.

Ma CA, Stinson JR, Zhang Y, Abbott JK, Weinreich MA, Hauk PJ, Reynolds PR, Lyons JJ, Nelson CG, Ruffo E, Dorjbal B, Glauzy S, Yamakawa N, Arjunaraja S, Voss K, Stoddard J, Niemela J, Zhang Y, Rosenzweig SD, McElwee JJ, DiMaggio T, Matthews HF, Jones N, Stone KD, Palma A, Oleastro M, Prieto E, Bernasconi AR, Dubra G, Danielian S, Zaiat J, Marti MA, Kim B, Cooper MA, Romberg N, Meffre E, Gelfand EW, Snow AL, Milner JD. Germline hypomorphic CARD11 mutations in severe atopic disease. Nat Genet. 2017 Aug;49(8):1192-1201. doi: 10.1038/ng.3898. Epub 2017 Jun 19. PubMed PMID: 28628108; PubMed Central PMCID: PMC5664152.

Leichner TM, Satake A, Harrison VS, Tanaka Y, Archambault AS, Kim BS, Siracusa MC, Leonard WJ, Naji A, Wu GF, Artis D, Kambayashi T. Skin-derived TSLP systemically expands regulatory T cells. J Autoimmun. 2017 May;79:39-52. doi: 10.1016/j.jaut.2017.01.003. Epub 2017 Jan 23. PubMed PMID: 28126203; PubMed Central PMCID: PMC5386815.

2016

Oetjen LK, Noti M, Kim BS. New insights into basophil heterogeneity. Semin Immunopathol. 2016 Sep;38(5):549-61. doi: 10.1007/s00281-016-0567-z. Epub 2016 May 13. Review. PubMed PMID: 27178409; PubMed Central PMCID: PMC5010479. Altmetric

Xu AZ, Tripathi SV, Kau AL, Schaffer A, Kim BS. Immune dysregulation underlies a subset of patients with chronic idiopathic pruritus. J Am Acad Dermatol. 2016 May;74(5):1017-20. doi: 10.1016/j.jaad.2015.11.029. PubMed PMID: 27085236; PubMed Central PMCID: PMC4834432. PlumX Metrics

Rak GD, Osborne LC, Siracusa MC, Kim BS, Wang K, Bayat A, Artis D, Volk SW. IL-33-Dependent Group 2 Innate Lymphoid Cells Promote Cutaneous Wound Healing. J Invest Dermatol. 2016 Feb;136(2):487-496. doi: 10.1038/JID.2015.406. PubMed PMID: 26802241; PubMed Central PMCID: PMC4731037.

Jariwala N, Benoit B, Kossenkov AV, Oetjen LK, Whelan TM, Cornejo CM, Takeshita J, Kim BS, Showe LC, Wysocka M, Rook AH. TIGIT and Helios Are Highly Expressed on CD4+ T Cells in Sézary Syndrome Patients. J Invest Dermatol. 2017 Jan;137(1):257-260. doi: 10.1016/j.jid.2016.08.016. Epub 2016 Sep 1. PubMed PMID: 27592800; PubMed Central PMCID: PMC5358509.

2015

Margolis DJ, Mitra N, Kim B, Gupta J, Hoffstad OJ, Papadopoulos M, Wubbenhorst B, Nathanson KL, Duke JL, Monos DS, Kamoun M. Association of HLA-DRB1 genetic variants with the persistence of atopic dermatitis. Hum Immunol. 2015 Aug;76(8):571-7. doi: 10.1016/j.humimm.2015.08.003. Epub 2015 Aug 22. PubMed PMID: 26307177; PubMed Central PMCID: PMC4593755.

2014

Kim BS, Wang K, Siracusa MC, Saenz SA, Brestoff JR, Monticelli LA, Noti M, Tait Wojno ED, Fung TC, Kubo M, Artis D. Basophils promote innate lymphoid cell responses in inflamed skin. J Immunol. 2014 Oct 1;193(7):3717-25. doi: 10.4049/jimmunol.1401307. Epub 2014 Aug 25. PubMed PMID: 25156365; PubMed Central PMCID: PMC4170007.

Kim BS. Innate lymphoid cells in the skin. J Invest Dermatol. 2015 Mar;135(3):673-678. doi: 10.1038/jid.2014.401. Epub 2014 Oct 23. Review. PubMed PMID: 25339380; PubMed Central PMCID: PMC4556524.

Kim BS, Artis D. Group 2 innate lymphoid cells in health and disease. Cold Spring Harb Perspect Biol. 2015 Jan 8;7(5). doi: 10.1101/cshperspect.a016337. Review. PubMed PMID: 25573713; PubMed Central PMCID: PMC4448620.

Brestoff JR, Kim BS, Saenz SA, Stine RR, Monticelli LA, Sonnenberg GF, Thome JJ, Farber DL, Lutfy K, Seale P, Artis D. Group 2 innate lymphoid cells promote beiging of white adipose tissue and limit obesity. Nature. 2015 Mar 12;519(7542):242-6. doi: 10.1038/nature14115. Epub 2014 Dec 22. PubMed PMID: 25533952; PubMed Central PMCID: PMC4447235.

Noti M, Kim BS, Siracusa MC, Rak GD, Kubo M, Moghaddam AE, Sattentau QA, Comeau MR, Spergel JM, Artis D. Exposure to food allergens through inflamed skin promotes intestinal food allergy through the thymic stromal lymphopoietin-basophil axis. J Allergy Clin Immunol. 2014 May;133(5):1390-9, 1399.e1-6. doi: 10.1016/j.jaci.2014.01.021. Epub 2014 Feb 20. PubMed PMID: 24560412; PubMed Central PMCID: PMC4007098.

Margolis DJ, Kim B, Apter AJ, Gupta J, Hoffstad O, Papadopoulos M, Mitra N. Thymic stromal lymphopoietin variation, filaggrin loss of function, and the persistence of atopic dermatitis. JAMA Dermatol. 2014 Mar;150(3):254-9. doi: 10.1001/jamadermatol.2013.7954. PubMed PMID: 24401911; PubMed Central PMCID: PMC4414492.

2013

Kim BS, Siracusa MC, Saenz SA, Noti M, Monticelli LA, Sonnenberg GF, Hepworth MR, Van Voorhees AS, Comeau MR, Artis D. TSLP elicits IL-33-independent innate lymphoid cell responses to promote skin inflammation. Sci Transl Med. 2013 Jan 30;5(170):170ra16. doi: 10.1126/scitranslmed.3005374. PMID: 23363980 Altmetric

Kim BS, Wojno ED, Artis D. Innate lymphoid cells and allergic inflammation. Curr Opin Immunol. 2013 Dec;25(6):738-44. doi: 10.1016/j.coi.2013.07.013. Epub 2013 Aug 31. Review. PubMed PMID: 24001372; PubMed Central PMCID: PMC3989991.

Siracusa MC, Saenz SA, Wojno ED, Kim BS, Osborne LC, Ziegler CG, Benitez AJ, Ruymann KR, Farber DL, Sleiman PM, Hakonarson H, Cianferoni A, Wang ML, Spergel JM, Comeau MR, Artis D. Thymic stromal lymphopoietin-mediated extramedullary hematopoiesis promotes allergic inflammation. Immunity. 2013 Dec 12;39(6):1158-70. doi: 10.1016/j.immuni.2013.09.016. PubMed PMID: 24332033; PubMed Central PMCID: PMC3959827.

Siracusa MC, Kim BS, Spergel JM, Artis D. Basophils and allergic inflammation. J Allergy Clin Immunol. 2013 Oct;132(4):789-801; quiz 788. doi: 10.1016/j.jaci.2013.07.046. Review. PubMed PMID: 24075190; PubMed Central PMCID: PMC3903395.

Saenz SA, Siracusa MC, Monticelli LA, Ziegler CG, Kim BS, Brestoff JR, Peterson LW, Wherry EJ, Goldrath AW, Bhandoola A, Artis D. IL-25 simultaneously elicits distinct populations of innate lymphoid cells and multipotent progenitor type 2 (MPPtype2) cells. J Exp Med. 2013 Aug 26;210(9):1823-37. doi: 10.1084/jem.20122332. Epub 2013 Aug 19. PubMed PMID: 23960191; PubMed Central PMCID: PMC3754870.

Noti M, Wojno ED, Kim BS, Siracusa MC, Giacomin PR, Nair MG, Benitez AJ, Ruymann KR, Muir AB, Hill DA, Chikwava KR, Moghaddam AE, Sattentau QJ, Alex A, Zhou C, Yearley JH, Menard-Katcher P, Kubo M, Obata-Ninomiya K, Karasuyama H, Comeau MR, Brown-Whitehorn T, de Waal Malefyt R, Sleiman PM, Hakonarson H, Cianferoni A, Falk GW, Wang ML, Spergel JM, Artis D. Thymic stromal lymphopoietin-elicited basophil responses promote eosinophilic esophagitis. Nat Med. 2013 Aug;19(8):1005-13. doi: 10.1038/nm.3281. Epub 2013 Jul 21. PubMed PMID: 23872715; PubMed Central PMCID: PMC3951204.

Roediger B, Kyle R, Yip KH, Sumaria N, Guy TV, Kim BS, Mitchell AJ, Tay SS, Jain R, Forbes-Blom E, Chen X, Tong PL, Bolton HA, Artis D, Paul WE, Fazekas de St Groth B, Grimbaldeston MA, Le Gros G, Weninger W. Cutaneous immunosurveillance and regulation of inflammation by group 2 innate lymphoid cells. Nat Immunol. 2013 Jun;14(6):564-73. doi: 10.1038/ni.2584. Epub 2013 Apr 21. PubMed PMID: 23603794; PubMed Central PMCID: PMC4282745.

2012 and Before

Keratinocytes function as accessory cells for presentation of endogenous antigen expressed in the epidermis. Kim BS, Miyagawa F, Cho YH, Bennett CL, Clausen BE, Katz SI. J Invest Dermatol. 2009 Dec;129(12):2805-17. doi: 10.1038/jid.2009.176. Epub 2009 Jun 25.PMID: 19554018 Plumx Metrics

Commensal bacteria-derived signals regulate basophil hematopoiesis and allergic inflammation. Hill DA, Siracusa MC, Abt MC, Kim BS, Kobuley D, Kubo M, Kambayashi T, Larosa DF, Renner ED, Orange JS, Bushman FD, Artis D. Nat Med. 2012 Mar 25;18(4):538-46. doi: 10.1038/nm.2657. PMID: 22447074

TSLP promotes interleukin-3-independent basophil haematopoiesis and type 2 inflammation. Siracusa MC, Saenz SA, Hill DA, Kim BS, Headley MB, Doering TA, Wherry EJ, Jessup HK, Siegel LA, Kambayashi T, Dudek EC, Kubo M, Cianferoni A, Spergel JM, Ziegler SF, Comeau MR, Artis D. Nature. 2011 Aug 14;477(7363):229-33. doi: 10.1038/nature10329. PMID: 21841801

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