Publications

Our Publications

We publish regularly in journals that cover a range of topics from fundamental basic science to large clinical trials. Please see below for a representative list of our publications.
Hussain M, Bonilla-Rosso G, Kwong Chung CKC, Bäriswyl L, Rodriguez MP, Kim BS, Engel P, Noti M. High dietary fat intake induces a microbiota signature that promotes food allergy. J Allergy Clin Immunol. 2019 Jul;144(1):157-170.e8. doi: 10.1016/j.jaci.2019.01.043. Epub 2019 Feb 13. PubMed PMID: 30768991.
Meixiong J, Anderson M, Limjunyawong N, Sabbagh MF, Hu E, Mack MR, Oetjen LK, Wang F, Kim BS, Dong X. Activation of Mast-Cell-Expressed Mas-Related G-Protein-Coupled Receptors Drives Non-histaminergic Itch. Immunity. 2019 May 21;50(5):1163-1171.e5. doi: 10.1016/j.immuni.2019.03.013. Epub 2019 Apr 23. PubMed PMID: 31027996; PubMed Central PMCID: PMC6531358.
Trier AM, Mack MR, Kim BS. The Neuroimmune Axis in Skin Sensation, Inflammation, and Immunity. J Immunol. 2019 May 15;202(10):2829-2835. doi: 10.4049/jimmunol.1801473. Review. PubMed PMID: 31061146; PubMed Central PMCID: PMC6563610.
Davidson WF, Leung DYM, Beck LA, Berin CM, Boguniewicz M, Busse WW, Chatila TA, Geha RS, Gern JE, Guttman-Yassky E, Irvine AD, Kim BS, Kong HH, Lack G, Nadeau KC, Schwaninger J, Simpson A, Simpson EL, Spergel JM, Togias A, Wahn U, Wood RA, Woodfolk JA, Ziegler SF, Plaut M. Report from the National Institute of Allergy and Infectious Diseases workshop on “Atopic dermatitis and the atopic march: Mechanisms and interventions”. J Allergy Clin Immunol. 2019 Mar;143(3):894-913. doi: 10.1016/j.jaci.2019.01.003. Epub 2019 Jan 9. PubMed PMID: 30639346; PubMed Central PMCID: PMC6905466.
Huang LH, Zinselmeyer BH, Chang CH, Saunders BT, Elvington A, Baba O, Broekelmann TJ, Qi L, Rueve JS, Swartz MA, Kim BS, Mecham RP, Wiig H, Thomas MJ, Sorci-Thomas MG, Randolph GJ. Interleukin-17 Drives Interstitial Entrapment of Tissue Lipoproteins in Experimental Psoriasis. Cell Metab. 2019 Feb 5;29(2):475-487.e7. doi: 10.1016/j.cmet.2018.10.006. Epub 2018 Nov 8. PubMed PMID: 30415924; PubMed Central PMCID: PMC6365189.
Erickson S, Kim BS. Research Techniques Made Simple: Itch Measurement in Clinical Trials. J Invest Dermatol. 2019 Feb;139(2):264-269.e1. doi: 10.1016/j.jid.2018.12.004. PubMed PMID: 30665580.
Mack MR, Kim BS. The Itch-Scratch Cycle: A Neuroimmune Perspective. Trends Immunol. 2018 Dec;39(12):980-991. doi: 10.1016/j.it.2018.10.001. Epub 2018 Nov 21. Review. PubMed PMID: 30471983.
Kesterson K, Nahmias Z, Brestoff JR, Bodet ND, Kau A, Kim BS. Generalized pruritus relieved by NSAIDs in the setting of mast cell activation syndrome. J Allergy Clin Immunol Pract. 2018 Nov – Dec;6(6):2130-2131. doi: 10.1016/j.jaip.2018.03.002. Epub 2018 Mar 23. PubMed PMID: 29577987; NIHMSID:NIHMS1543467.
Trier AM, Kim BS. Cytokine modulation of atopic itch. Curr Opin Immunol. 2018 Oct;54:7-12. doi: 10.1016/j.coi.2018.05.005. Epub 2018 Jun 21. Review. PubMed PMID: 29935376.
Oetjen LK, Kim BS. Interactions of the immune and sensory nervous systems in atopy. FEBS J. 2018 Sep;285(17):3138-3151. doi: 10.1111/febs.14465. Epub 2018 Apr 30. Review. PubMed PMID: 29637705; PubMed Central PMCID: PMC6516504.
Hoye ML, Archambault AS, Gordon TM, Oetjen LK, Cain MD, Klein RS, Crosby SD, Kim BS, Miller TM, Wu GF. MicroRNA signature of central nervous system-infiltrating dendritic cells in an animal model of multiple sclerosis. Immunology. 2018 Sep;155(1):112-122. doi: 10.1111/imm.12934. Epub 2018 May 10. PubMed PMID: 29749614; PubMed Central PMCID: PMC6099169.
Brestoff JR, Tesfazghi MT, Zaydman MA, Jackups R Jr, Kim BS, Scott MG, Gronowski AM, Grossman BJ. The B antigen protects against the development of red meat allergy. J Allergy Clin Immunol Pract. 2018 Sep – Oct;6(5):1790-1791.e3. doi: 10.1016/j.jaip.2018.02.010. Epub 2018 Mar 3. PubMed PMID: 29510233.
Shepherd AJ, Mickle AD, Golden JP, Mack MR, Halabi CM, de Kloet AD, Samineni VK, Kim BS, Krause EG, Gereau RW 4th, Mohapatra DP. Macrophage angiotensin II type 2 receptor triggers neuropathic pain. Proc Natl Acad Sci U S A. 2018 Aug 21;115(34):E8057-E8066. doi: 10.1073/pnas.1721815115. Epub 2018 Aug 6. PubMed PMID: 30082378; PubMed Central PMCID: PMC6112686.
Luo J, Qian A, Oetjen LK, Yu W, Yang P, Feng J, Xie Z, Liu S, Yin S, Dryn D, Cheng J, Riehl TE, Zholos AV, Stenson WF, Kim BS, Hu H. TRPV4 Channel Signaling in Macrophages Promotes Gastrointestinal Motility via Direct Effects on Smooth Muscle Cells.Immunity. 2018 Jul 17;49(1):107-119.e4. doi: 10.1016/j.immuni.2018.04.021. Epub 2018 Jun 26. PubMed PMID: 29958798; PubMed Central PMCID: PMC6051912.
Morris GM, Nahmias ZP, Kim BS. Simultaneous improvement of alopecia universalis and atopic dermatitis in a patient treated with a JAK inhibitor. JAAD Case Rep. 2018 Jul;4(6):515-517. doi: 10.1016/j.jdcr.2017.12.016. eCollection 2018 Jul. PubMed PMID: 30023415; PubMed Central PMCID: PMC6047104.
Margolis DJ, Mitra N, Gochnauer H, Wubbenhorst B, D’Andrea K, Kraya A, Hoffstad O, Gupta J, Kim B, Yan A, Fuxench ZC, Nathanson KL. Uncommon Filaggrin Variants Are Associated with Persistent Atopic Dermatitis in African Americans. J Invest Dermatol. 2018 Jul;138(7):1501-1506. doi: 10.1016/j.jid.2018.01.029. Epub 2018 Feb 8. PubMed PMID: 29428354; PubMed Central PMCID: PMC6272058.
Perry JSA, Russler-Germain EV, Zhou YW, Purtha W, Cooper ML, Choi J, Schroeder MA, Salazar V, Egawa T, Lee BC, Abumrad NA, Kim BS, Anderson MS, DiPersio JF, Hsieh CS. Transfer of Cell-Surface Antigens by Scavenger Receptor CD36 Promotes Thymic Regulatory T Cell Receptor Repertoire Development and Allo-tolerance. Immunity. 2018 Jun 19;48(6):1271. doi: 10.1016/j.immuni.2018.05.011. PubMed PMID: 29924978; PubMed Central PMCID: PMC6015728.
Feng J, Luo J, Yang P, Du J, Kim BS, Hu H. Piezo2 channel-Merkel cell signaling modulates the conversion of touch to itch.Science. 2018 May 4;360(6388):530-533. doi: 10.1126/science.aar5703. PubMed PMID: 29724954; PubMed Central PMCID: PMC6114129.
Luo J, Feng J, Yu G, Yang P, Mack MR, Du J, Yu W, Qian A, Zhang Y, Liu S, Yin S, Xu A, Cheng J, Liu Q, O’Neil RG, Xia Y, Ma L, Carlton SM, Kim BS, Renner K, Liu Q, Hu H. Transient receptor potential vanilloid 4-expressing macrophages and keratinocytes contribute differentially to allergic and nonallergic chronic itch. J Allergy Clin Immunol. 2018 Feb;141(2):608-619.e7. doi: 10.1016/j.jaci.2017.05.051. Epub 2017 Aug 11. PubMed PMID: 28807414; PubMed Central PMCID: PMC5799031.
Meisel JS, Sfyroera G, Bartow-McKenney C, Gimblet C, Bugayev J, Horwinski J, Kim B, Brestoff JR, Tyldsley AS, Zheng Q, Hodkinson BP, Artis D, Grice EA. Commensal microbiota modulate gene expression in the skin. Microbiome. 2018 Jan 30;6(1):20. doi: 10.1186/s40168-018-0404-9. PubMed PMID: 29378633; PubMed Central PMCID: PMC5789709.
Hussain M, Borcard L, Walsh KP, Pena Rodriguez M, Mueller C, Kim BS, Kubo M, Artis D, Noti M. Basophil-derived IL-4 promotes epicutaneous antigen sensitization concomitant with the development of food allergy. J Allergy Clin Immunol.2018 Jan;141(1):223-234.e5. doi: 10.1016/j.jaci.2017.02.035. Epub 2017 Apr 6. PubMed PMID: 28390860.
Feng J, Yang P, Mack MR, Dryn D, Luo J, Gong X, Liu S, Oetjen LK, Zholos AV, Mei Z, Yin S, Kim BS, Hu H. Sensory TRP channels contribute differentially to skin inflammation and persistent itch. Nat Commun. 2017 Oct 30;8(1):980. doi: 10.1038/s41467-017-01056-8. PubMed PMID: 29081531; PubMed Central PMCID: PMC5661746.
Oetjen LK, Mack MR, Feng J, Whelan TM, Niu H, Guo CJ, Chen S, Trier AM, Xu AZ, Tripathi SV, Luo J, Gao X, Yang L, Hamilton SL, Wang PL, Brestoff JR, Council ML, Brasington R, Schaffer A, Brombacher F, Hsieh CS, Gereau RW 4th, Miller MJ, Chen ZF, Hu H, Davidson S, Liu Q, Kim BS. Sensory Neurons Co-opt Classical Immune Signaling Pathways to Mediate Chronic Itch. Cell. 2017 Sep 21;171(1):217-228.e13. doi: 10.1016/j.cell.2017.08.006. Epub 2017 Sep 7. PubMed PMID: 28890086; PubMed Central PMCID: PMC5658016.
Feng J, Luo J, Mack MR, Yang P, Zhang F, Wang G, Gong X, Cai T, Mei Z, Kim BS, Yin S, Hu H. The antimicrobial peptide human beta-defensin 2 promotes itch through Toll-like receptor 4 signaling in mice. J Allergy Clin Immunol. 2017 Sep;140(3):885-888.e6. doi: 10.1016/j.jaci.2017.03.035. Epub 2017 Apr 23. PubMed PMID: 28442325; PubMed Central PMCID: PMC5591760.
Ma CA, Stinson JR, Zhang Y, Abbott JK, Weinreich MA, Hauk PJ, Reynolds PR, Lyons JJ, Nelson CG, Ruffo E, Dorjbal B, Glauzy S, Yamakawa N, Arjunaraja S, Voss K, Stoddard J, Niemela J, Zhang Y, Rosenzweig SD, McElwee JJ, DiMaggio T, Matthews HF, Jones N, Stone KD, Palma A, Oleastro M, Prieto E, Bernasconi AR, Dubra G, Danielian S, Zaiat J, Marti MA, Kim B, Cooper MA, Romberg N, Meffre E, Gelfand EW, Snow AL, Milner JD. Germline hypomorphic CARD11 mutations in severe atopic disease.Nat Genet. 2017 Aug;49(8):1192-1201. doi: 10.1038/ng.3898. Epub 2017 Jun 19. PubMed PMID: 28628108; PubMed Central PMCID: PMC5664152.
Leichner TM, Satake A, Harrison VS, Tanaka Y, Archambault AS, Kim BS, Siracusa MC, Leonard WJ, Naji A, Wu GF, Artis D, Kambayashi T. Skin-derived TSLP systemically expands regulatory T cells. J Autoimmun. 2017 May;79:39-52. doi: 10.1016/j.jaut.2017.01.003. Epub 2017 Jan 23. PubMed PMID: 28126203; PubMed Central PMCID: PMC5386815.
Jariwala N, Benoit B, Kossenkov AV, Oetjen LK, Whelan TM, Cornejo CM, Takeshita J, Kim BS, Showe LC, Wysocka M, Rook AH.TIGIT and Helios Are Highly Expressed on CD4+ T Cells in Sézary Syndrome Patients. J Invest Dermatol. 2017 Jan;137(1):257-260. doi: 10.1016/j.jid.2016.08.016. Epub 2016 Sep 1. PubMed PMID: 27592800; PubMed Central PMCID: PMC5358509.
Oetjen LK, Noti M, Kim BS. New insights into basophil heterogeneity. Semin Immunopathol. 2016 Sep;38(5):549-61. doi: 10.1007/s00281-016-0567-z. Epub 2016 May 13. Review. PubMed PMID: 27178409; PubMed Central PMCID: PMC5010479.
Xu AZ, Tripathi SV, Kau AL, Schaffer A, Kim BS. Immune dysregulation underlies a subset of patients with chronic idiopathic pruritus. J Am Acad Dermatol. 2016 May;74(5):1017-20. doi: 10.1016/j.jaad.2015.11.029. PubMed PMID: 27085236; PubMed Central PMCID: PMC4834432.
Rak GD, Osborne LC, Siracusa MC, Kim BS, Wang K, Bayat A, Artis D, Volk SW. IL-33-Dependent Group 2 Innate Lymphoid Cells Promote Cutaneous Wound Healing. J Invest Dermatol. 2016 Feb;136(2):487-496. doi: 10.1038/JID.2015.406. PubMed PMID: 26802241; PubMed Central PMCID: PMC4731037.
Margolis DJ, Mitra N, Kim B, Gupta J, Hoffstad OJ, Papadopoulos M, Wubbenhorst B, Nathanson KL, Duke JL, Monos DS, Kamoun M. Association of HLA-DRB1 genetic variants with the persistence of atopic dermatitis. Hum Immunol. 2015 Aug;76(8):571-7. doi: 10.1016/j.humimm.2015.08.003. Epub 2015 Aug 22. PubMed PMID: 26307177; PubMed Central PMCID: PMC4593755.
Brestoff JR, Kim BS, Saenz SA, Stine RR, Monticelli LA, Sonnenberg GF, Thome JJ, Farber DL, Lutfy K, Seale P, Artis D. Group 2 innate lymphoid cells promote beiging of white adipose tissue and limit obesity. Nature. 2015 Mar 12;519(7542):242-6. doi: 10.1038/nature14115. Epub 2014 Dec 22. PubMed PMID: 25533952; PubMed Central PMCID: PMC4447235.
Kim BS. Innate lymphoid cells in the skin. J Invest Dermatol. 2015 Mar;135(3):673-678. doi: 10.1038/jid.2014.401. Epub 2014 Oct 23. Review. PubMed PMID: 25339380; PubMed Central PMCID: PMC4556524.
Kim BS, Artis D. Group 2 innate lymphoid cells in health and disease. Cold Spring Harb Perspect Biol. 2015 Jan 8;7(5). doi: 10.1101/cshperspect.a016337. Review. PubMed PMID: 25573713; PubMed Central PMCID: PMC4448620.
Kim BS, Wang K, Siracusa MC, Saenz SA, Brestoff JR, Monticelli LA, Noti M, Tait Wojno ED, Fung TC, Kubo M, Artis D. Basophils promote innate lymphoid cell responses in inflamed skin. J Immunol. 2014 Oct 1;193(7):3717-25. doi: 10.4049/jimmunol.1401307. Epub 2014 Aug 25. PubMed PMID: 25156365; PubMed Central PMCID: PMC4170007.
Noti M, Kim BS, Siracusa MC, Rak GD, Kubo M, Moghaddam AE, Sattentau QA, Comeau MR, Spergel JM, Artis D. Exposure to food allergens through inflamed skin promotes intestinal food allergy through the thymic stromal lymphopoietin-basophil axis. J Allergy Clin Immunol. 2014 May;133(5):1390-9, 1399.e1-6. doi: 10.1016/j.jaci.2014.01.021. Epub 2014 Feb 20. PubMed PMID: 24560412; PubMed Central PMCID: PMC4007098.
Margolis DJ, Kim B, Apter AJ, Gupta J, Hoffstad O, Papadopoulos M, Mitra N. Thymic stromal lymphopoietin variation, filaggrin loss of function, and the persistence of atopic dermatitis. JAMA Dermatol. 2014 Mar;150(3):254-9. doi: 10.1001/jamadermatol.2013.7954. PubMed PMID: 24401911; PubMed Central PMCID: PMC4414492.
Siracusa MC, Saenz SA, Wojno ED, Kim BS, Osborne LC, Ziegler CG, Benitez AJ, Ruymann KR, Farber DL, Sleiman PM, Hakonarson H, Cianferoni A, Wang ML, Spergel JM, Comeau MR, Artis D. Thymic stromal lymphopoietin-mediated extramedullary hematopoiesis promotes allergic inflammation. Immunity. 2013 Dec 12;39(6):1158-70. doi: 10.1016/j.immuni.2013.09.016. PubMed PMID: 24332033; PubMed Central PMCID: PMC3959827.
Kim BS, Wojno ED, Artis D. Innate lymphoid cells and allergic inflammation. Curr Opin Immunol. 2013 Dec;25(6):738-44. doi: 10.1016/j.coi.2013.07.013. Epub 2013 Aug 31. Review. PubMed PMID: 24001372; PubMed Central PMCID: PMC3989991.
Siracusa MC, Kim BS, Spergel JM, Artis D. Basophils and allergic inflammation. J Allergy Clin Immunol. 2013 Oct;132(4):789-801; quiz 788. doi: 10.1016/j.jaci.2013.07.046. Review. PubMed PMID: 24075190; PubMed Central PMCID: PMC3903395.
Saenz SA, Siracusa MC, Monticelli LA, Ziegler CG, Kim BS, Brestoff JR, Peterson LW, Wherry EJ, Goldrath AW, Bhandoola A, Artis D. IL-25 simultaneously elicits distinct populations of innate lymphoid cells and multipotent progenitor type 2 (MPPtype2) cells. J Exp Med. 2013 Aug 26;210(9):1823-37. doi: 10.1084/jem.20122332. Epub 2013 Aug 19. PubMed PMID: 23960191; PubMed Central PMCID: PMC3754870.
Noti M, Wojno ED, Kim BS, Siracusa MC, Giacomin PR, Nair MG, Benitez AJ, Ruymann KR, Muir AB, Hill DA, Chikwava KR, Moghaddam AE, Sattentau QJ, Alex A, Zhou C, Yearley JH, Menard-Katcher P, Kubo M, Obata-Ninomiya K, Karasuyama H, Comeau MR, Brown-Whitehorn T, de Waal Malefyt R, Sleiman PM, Hakonarson H, Cianferoni A, Falk GW, Wang ML, Spergel JM, Artis D. Thymic stromal lymphopoietin-elicited basophil responses promote eosinophilic esophagitis. Nat Med. 2013 Aug;19(8):1005-13. doi: 10.1038/nm.3281. Epub 2013 Jul 21. PubMed PMID: 23872715; PubMed Central PMCID: PMC3951204.
Roediger B, Kyle R, Yip KH, Sumaria N, Guy TV, Kim BS, Mitchell AJ, Tay SS, Jain R, Forbes-Blom E, Chen X, Tong PL, Bolton HA, Artis D, Paul WE, Fazekas de St Groth B, Grimbaldeston MA, Le Gros G, Weninger W. Cutaneous immunosurveillance and regulation of inflammation by group 2 innate lymphoid cells. Nat Immunol. 2013 Jun;14(6):564-73. doi: 10.1038/ni.2584. Epub 2013 Apr 21. PubMed PMID: 23603794; PubMed Central PMCID: PMC4282745.